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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB1
All Species:
43.33
Human Site:
T256
Identified Species:
68.1
UniProt:
P23443
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23443
NP_003152.1
525
59140
T256
V
T
H
T
F
C
G
T
I
E
Y
M
A
P
E
Chimpanzee
Pan troglodytes
XP_523815
451
50966
G213
L
G
H
L
H
Q
K
G
I
I
Y
R
D
L
K
Rhesus Macaque
Macaca mulatta
XP_001109701
525
59511
T256
V
T
H
T
F
C
G
T
I
E
Y
M
A
P
E
Dog
Lupus familis
XP_537702
525
59107
T256
V
T
H
T
F
C
G
T
I
E
Y
M
A
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSK8
525
59199
T256
V
T
H
T
F
C
G
T
I
E
Y
M
A
P
E
Rat
Rattus norvegicus
P67999
525
59113
T256
V
T
H
T
F
C
G
T
I
E
Y
M
A
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
T213
V
T
H
T
F
C
G
T
I
E
Y
M
A
P
E
Chicken
Gallus gallus
P18652
752
84421
T243
K
A
Y
S
F
C
G
T
V
E
Y
M
A
P
E
Frog
Xenopus laevis
P10666
629
71268
T225
K
A
Y
S
F
C
G
T
V
E
Y
M
A
P
E
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
T230
K
A
Y
S
F
C
G
T
V
E
Y
M
A
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
E430
H
S
F
C
G
T
L
E
Y
M
A
P
E
I
I
Honey Bee
Apis mellifera
XP_395876
456
51514
L217
I
K
L
T
D
F
G
L
C
K
E
H
I
Q
D
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
T267
K
T
Y
S
F
C
G
T
V
E
Y
M
A
P
E
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
T237
M
T
H
T
F
C
G
T
I
E
Y
M
A
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
L225
D
F
I
N
G
G
H
L
F
F
Q
L
Y
H
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
94.2
99.8
N.A.
99.2
99.6
N.A.
90.2
31.9
36.8
32.2
N.A.
20.8
54.6
31.2
59
Protein Similarity:
100
85.9
95.6
100
N.A.
99.4
99.6
N.A.
90.8
46.6
52.7
46.6
N.A.
31.3
68
43.6
70.8
P-Site Identity:
100
20
100
100
N.A.
100
100
N.A.
100
66.6
66.6
66.6
N.A.
0
13.3
73.3
93.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
100
86.6
86.6
86.6
N.A.
6.6
33.3
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
0
0
0
0
0
7
0
74
0
0
% A
% Cys:
0
0
0
7
0
74
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
7
% D
% Glu:
0
0
0
0
0
0
0
7
0
74
7
0
7
0
74
% E
% Phe:
0
7
7
0
74
7
0
0
7
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
14
7
80
7
0
0
0
0
0
0
0
% G
% His:
7
0
54
0
7
0
7
0
0
0
0
7
0
7
0
% H
% Ile:
7
0
7
0
0
0
0
0
54
7
0
0
7
7
7
% I
% Lys:
27
7
0
0
0
0
7
0
0
7
0
0
0
0
7
% K
% Leu:
7
0
7
7
0
0
7
14
0
0
0
7
0
7
0
% L
% Met:
7
0
0
0
0
0
0
0
0
7
0
74
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
7
0
74
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
7
0
0
7
7
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% R
% Ser:
0
7
0
27
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
54
0
54
0
7
0
74
0
0
0
0
0
0
0
% T
% Val:
40
0
0
0
0
0
0
0
27
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
27
0
0
0
0
0
7
0
80
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _